⸻ Longevity Medicine · Monarka Clinic Barcelona

Plasmapheresis.
A longevity tool.

Deep purification of blood plasma to reduce the burden of accumulated environmental factors, decrease chronic inflammation, and prepare the body for its maximum regenerative potential. Prescribed by our specialist when indicated.

60–100'

Duration per session

Recommended annual session

5.000€

All inclusive

⸻ What is it?

Plasma purification at a molecular level

Plasmapheresis is an advanced medical procedure that extracts blood, separates the plasma — the liquid component where toxins, altered proteins, and inflammatory molecules circulate — and replaces it with a clean and safe albumin solution.

At Monarka, we specifically perform therapeutic plasma exchange — the modality in which plasma is removed and replaced with albumin, eliminating unwanted substances and restoring the body’s protein balance. It is the modality with the strongest clinical evidence for therapeutic and longevity applications.

The result is a body with a lower inflammatory burden and a greater capacity to respond to regenerative treatments.

01

Extraction

The blood leaves the body through a venous route and is directed to our state-of-the-art centrifugation technology, which preserves cellular integrity.

02

Separation and purification

The machine separates the plasma from the other components (red blood cells, platelets). The purified plasma contains the substances to be eliminated; healthy cells are preserved.

03

Replacement and return

The removed plasma is replaced with albumin, a highly tolerable protein. The purified blood is continuously returned to the body via the venous return line.

⸻ What eliminates

What you accumulate without
realizing it

We live in an environment with an unprecedented toxic load. The body has elimination mechanisms, but these become overwhelmed. Plasmapheresis acts where the liver and kidneys can no longer do it alone.

Microplastics

Already detected in the blood of most adults. Their presence generates silent inflammation and sustained oxidative stress.

Glycosylated and oxidized proteins

Directly responsible for accelerated aging and progressive cellular dysfunction.

Pesticides and chemical waste

Originating from conventional food, with a cumulative effect over the years.

Heavy metals and environmental toxins

Pollution, industrial pollutants and endocrine disruptors that we breathe every day in urban environments.

Pro-inflammatory molecules

Cytokines, immune complexes, and other mediators that maintain the body in a state of chronic low-grade inflammation.

“The body has very efficient elimination mechanisms, but in the current environment these systems can become overwhelmed. Plasmapheresis is a medical tool to support this cleansing capacity.”

Monarka Clinic Medical Team · Barcelona

Ideal candidate profile

⸻ Clinical indications

Who is it indicated for?

Plasmapheresis has applications both in preventive longevity medicine and in the treatment of specific pathologies with an inflammatory or autoimmune component.

Longevity and performance

For those who want to optimize their biology: reduce baseline inflammation, improve cellular energy, and prepare the body to respond better to regenerative treatments.

Longevity

Autoimmune diseases

Multiple sclerosis, lupus erythematosus, myasthenia gravis, Guillain-Barré syndrome. Plasmapheresis can help eliminate autoantibodies involved in the immune attack, as a complementary therapy and always under specialized medical supervision, without replacing the primary treatment.

Complementary · Medical supervision

Chronic fatigue and brain fog

When toxic saturation affects cognitive clarity and energy levels, plasma clearance can restore a cleaner, more functional metabolic environment.

Longevity

Liver and kidney overload

When the liver and kidneys are overloaded, plasmapheresis acts as external support to their cleansing functions, reducing the workload and promoting their recovery.

Metabolic

Chronic systemic inflammation

Low-grade inflammation is the common denominator of most chronic diseases. Removing pro-inflammatory molecules from the plasma is one of the most direct interventions available.

Metabolic

Enhancement of regenerative treatments

When the specialist determines that it is indicated, plasmapheresis improves the response to other protocols of the Monarka Plan: cell therapy, precision supplementation and biological activation programs respond better in an organism with a lower inflammatory load.

Longevity

01

Approved procedure

Established medical protocol with proven clinical evidence

02

Advanced Centrifugation

State-of-the-art technology that preserves cellular integrity

03

Medical supervision

Conducted by longevity specialists throughout the session

04

Immediate recovery

No rest required · Normal activity on the same day

05

Sterile material

Closed circuit, single use per session

Px

1

2

3

Plasmapheresis · If indicated by the specialist

When indicated, plasma purification significantly enhances the effectiveness of the regenerative protocols in the plan. It is not a mandatory step, but rather a high-impact tool.

Prescribed after medical evaluation

Precision diagnostics

Advanced analytics, biomarker evaluation, and customized protocol design.

Movement · Food · Thought

Activation of the three pillars of the Monarka Methodology with individualized protocols.

Regenerative treatments

IHHT, cell therapies, precision supplementation, and biological activation protocols.

Continuous monitoring and optimization

Periodic reviews, protocol adjustments, and long-term maintenance of results.

⸻ Monarka Methodology

Integrated into your Monarka Plan when appropriate

At Monarka, we don’t offer standard treatments. After an initial assessment with our longevity specialist, we determine if plasmapheresis is right for you and at what point in your plan it makes the most sense to incorporate it.

When indicated, it acts as a powerful tool: by purifying the plasma, the body responds better to the regenerative protocols that are part of your personalized plan.

Prescribed if indicated

Motion

Food

Thought

Px

1

2

3

Plasmapheresis · If indicated by the specialist

When indicated, plasma purification significantly enhances the effectiveness of the regenerative protocols in the plan. It is not a mandatory step, but rather a high-impact tool.

Prescribed after medical evaluation

Precision diagnostics

Advanced analytics, biomarker evaluation, and customized protocol design.

Movement · Food · Thought

Activation of the three pillars of the Monarka Methodology with individualized protocols.

Regenerative treatments

IHHT, cell therapies, precision supplementation, and biological activation protocols.

Continuous monitoring and optimization

Periodic reviews, protocol adjustments, and long-term maintenance of results.

⸻ Monarka Methodology

Integrated into your Monarka Plan when appropriate

At Monarka, we don’t offer standard treatments. After an initial assessment with our longevity specialist, we determine if plasmapheresis is right for you and at what point in your plan it makes the most sense to incorporate it.

When indicated, it acts as a powerful tool: by purifying the plasma, the body responds better to the regenerative protocols that are part of your personalized plan.

Prescribed if indicated

Motion

Food

Thought

What you can expect

The results are progressive and are noticeable in the medium to long term. The effects may vary depending on each patient’s individual profile and the overall protocol followed.

Increased energy and vitality

Reducing the inflammatory burden can free up metabolic resources that the body was using to manage that inflammation. Many patients report a progressive and sustained improvement in energy levels.

Mental clarity

Some patients report improved cognitive clarity and concentration, associated with a reduction in systemic inflammation. Individual results may vary.

Better regenerative response

By reducing factors that can inhibit cell regeneration, the body can respond more effectively to subsequent regenerative protocols of the Monarka Plan.

Reduction of systemic inflammation

Low-grade chronic inflammation is linked to accelerated aging and numerous chronic diseases. Plasmapheresis acts directly and measurably on this factor.

Support for liver and kidney function

By reducing the workload on the liver and kidneys, these organs can function more efficiently. Overall metabolism gradually returns to a more balanced state.

Sustained results

The benefits are noticeable in the medium and long term. With one session per year and by maintaining the habits developed in the Monarka Plan, the detoxifying effect is maintained and enhanced.

⸻ Frequently Asked Questions

Everything you need to know

Not exactly, although in clinical practice they are often used interchangeably. Plasmapheresis is the general term for any procedure that separates plasma from the blood — including, for example, plasma donation. Therapeutic plasma exchange is its specific clinical application: the patient’s plasma is removed and replaced with albumin or another substitute, eliminating unwanted substances and restoring protein balance. This is precisely what we perform at Monarka, and it is the modality with the strongest evidence for therapeutic and longevity use.

The duration depends on individual factors such as weight, height, and hematocrit. Generally, each session lasts between 60 and 100 minutes, with a maximum of approximately 2 hours. Recovery is immediate: you can resume your normal activities the same day without needing to rest.

As part of a longevity plan, one session per year is typically recommended for maintenance. The exact number and frequency of sessions are determined during the initial medical assessment, based on the patient’s health status, goals, and overall protocol.

Yes. Plasmapheresis is an established and validated medical procedure, performed at Monarka by specialized professionals using high-precision centrifugation technology. The main possible side effect is the appearance of a slight bruise at the puncture site, as with any venous access. It is very well tolerated by the vast majority of patients.

The Monarka medical team will provide you with specific guidelines during your initial assessment. Generally, adequate hydration is recommended, and you should avoid fasting. A preliminary blood test is performed to confirm that the treatment is appropriate and to tailor the protocol to your individual needs.

Plasmapheresis is not a mandatory or automatic step in the Monarka Plan, but rather a tool that the longevity specialist prescribes when it is indicated for your individual profile. After the initial assessment—which includes blood tests if necessary—the doctor determines whether and when it makes sense to incorporate it. When indicated, its cleansing effect significantly enhances the response to the other protocols in the plan: precision nutrition, supplementation, HHT (Heat-Hypertension Therapy), and cell therapies.

The price of a plasmapheresis session at Monarka Clinic is €5,000. This price includes the initial consultation with our longevity specialist, any necessary blood tests if the medical team deems them appropriate, and the complete plasmapheresis session. There are no hidden costs or additional charges.

Plasmapheresis acts at the molecular level directly on the blood, eliminating substances that no supplement, diet, or detox protocol can reach: microplastics, glycated proteins, autoantibodies, and environmental toxins that accumulate in the plasma. It is not comparable to any nutritional or lifestyle intervention.

Assessment included in the treatment

The plasmapheresis session at Monarka includes a prior consultation with our longevity specialist: we evaluate your profile, review your history, and design how to integrate the treatment into your personal Monarka Plan.

Total price · All inclusive

5.000 €

Response in less than 24 hours

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Is plasmapheresis
the tool you need?

There’s only one way to know: an assessment with our longevity specialist. When it’s indicated, it’s one of the most powerful interventions we can offer. When it’s not, we’ll tell you.