⸻ Longevity Medicine · Monarka Clinic Barcelona
Plasmapheresis in Barcelona.
A longevity
tool.
Therapeutic plasma exchange in Barcelona: part of the plasma is removed from your blood and replaced with albumin, within a longevity strategy. Prescribed by our specialist when indicated.
60–100'
Duration per session
1×
Recommended annual session
5.000€
All inclusive
⸻ What is it?
Plasma purification at a molecular level
Plasmapheresis is an advanced medical procedure that extracts blood, separates the plasma — the liquid component where toxins, altered proteins, and inflammatory molecules circulate — and replaces it with a clean and safe albumin solution.
At Monarka, we specifically perform therapeutic plasma exchange — the modality in which plasma is removed and replaced with albumin, eliminating unwanted substances and restoring the body’s protein balance. It is the modality used in hospitals for its recognized medical indications.
The aim is to lower the load of certain molecules in the plasma. Its effect in healthy people is still being studied.
Want to see the studies? Read our guide: plasmapheresis: what it is, what it is for and what the evidence says.
01
Extraction
The blood leaves the body through a venous route and is directed to our state-of-the-art centrifugation technology, which preserves cellular integrity.
02
Separation and purification
The machine separates the plasma from the other components (red blood cells, platelets). The purified plasma contains the substances to be eliminated; healthy cells are preserved.
03
Replacement and return
The removed plasma is replaced with albumin, a highly tolerable protein. The purified blood is continuously returned to the body via the venous return line.
⸻ What is removed
What is in the plasma
We are exposed to substances in our environment. The liver and kidneys remove most of them. Plasmapheresis removes part of the proteins and molecules in the plasma, but it does not replace any organ.
Microplastics
Detected in adult blood in several studies. It is still not clear what effect they have on health, or whether removing them from the plasma brings any benefit.
Glycosylated and oxidized proteins
Linked to aging and inflammation. Their exact role is still being studied.
Pesticides and chemical waste
Originating from conventional food, with a cumulative effect over the years.
Heavy metals and environmental toxins
Pollution, industrial pollutants and endocrine disruptors that we breathe every day in urban environments.
Pro-inflammatory molecules
Cytokines, immune complexes, and other mediators that maintain the body in a state of chronic low-grade inflammation.
“The body has very efficient elimination mechanisms, but in the current environment these systems can become overwhelmed. Plasmapheresis is a medical tool to support this cleansing capacity.”
Monarka Clinic Medical Team · Barcelona
Ideal candidate profile
- People with chronic fatigue of no apparent cause
- High environmental or dietary exposure to toxins
- Systemic inflammation or elevated biomarkers
- Patients starting a Monarka longevity plan
- Autoimmune or metabolic diseases under treatment
⸻ Clinical indications
Who is it indicated for?
Plasmapheresis has applications both in preventive longevity medicine and in the treatment of specific pathologies with an inflammatory or autoimmune component.
Longevity and performance
For people who want to include it in a preventive longevity strategy. The evidence in healthy people is still preliminary, and the specialist assesses your case before proposing it.
Longevity
Autoimmune diseases
Multiple sclerosis, lupus erythematosus, myasthenia gravis, Guillain-Barré syndrome. Plasmapheresis can help eliminate autoantibodies involved in the immune attack, as a complementary therapy and always under specialized medical supervision, without replacing the primary treatment.
Complementary · Medical supervision
Chronic fatigue and brain fog
Chronic fatigue has many causes. The data on plasmapheresis in this case are preliminary, and the specialist assesses your case before proposing it.
Longevity
Liver and kidney overload
Only the specialist can assess whether your blood tests justify it. Plasmapheresis does not replace any liver or kidney treatment.
Metabolic
Chronic systemic inflammation
Low-grade inflammation is linked to many chronic diseases. Studies on plasmapheresis in this field are under way, but the evidence is still limited.
Metabolic
Enhancement of regenerative treatments
When the specialist determines that it is indicated, it can be part of other Monarka Plan protocols: cell therapy, precision supplementation and biological activation programs. No studies show that it improves their response.
Longevity
01
Established procedure
Used in hospitals for decades. In longevity, the evidence is still preliminary
02
Advanced Centrifugation
State-of-the-art technology that preserves cellular integrity
03
Medical supervision
Conducted by longevity specialists throughout the session
04
Immediate recovery
No rest required · Normal activity on the same day
05
Sterile material
Closed circuit, single use per session
Px
1
2
3
∞
Plasmapheresis · If indicated by the specialist
When the specialist indicates it, it can be part of the plan's protocols. It is not a mandatory step.
Prescribed after medical evaluation
Precision diagnostics
Advanced analytics, biomarker evaluation, and customized protocol design.
Movement · Food · Thought
Activation of the three pillars of the Monarka Methodology with individualized protocols.
Regenerative treatments
IHHT, cell therapies, precision supplementation, and biological activation protocols.
Continuous monitoring and optimization
Periodic reviews, protocol adjustments, and long-term maintenance of results.
⸻ Monarka Methodology
Integrated into your Monarka Plan when appropriate
At Monarka, we don’t offer standard treatments. After an initial assessment with our longevity specialist, we determine if plasmapheresis is right for you and at what point in your plan it makes the most sense to incorporate it.
When indicated, it fits in with the regenerative protocols of your personalized plan.
Prescribed if indicated
Motion
Food
Thought
Px
1
2
3
∞
Plasmapheresis · If indicated by the specialist
When the specialist indicates it, it can be part of the plan's protocols. It is not a mandatory step.
Prescribed after medical evaluation
Precision diagnostics
Advanced analytics, biomarker evaluation, and customized protocol design.
Movement · Food · Thought
Activation of the three pillars of the Monarka Methodology with individualized protocols.
Regenerative treatments
IHHT, cell therapies, precision supplementation, and biological activation protocols.
Continuous monitoring and optimization
Periodic reviews, protocol adjustments, and long-term maintenance of results.
⸻ Monarka Methodology
Integrated into your Monarka Plan when appropriate
At Monarka, we don’t offer standard treatments. After an initial assessment with our longevity specialist, we determine if plasmapheresis is right for you and at what point in your plan it makes the most sense to incorporate it.
When indicated, it fits in with the regenerative protocols of your personalized plan.
Prescribed if indicated
Motion
Food
Thought
⸻ Results
What you can expect
The results are progressive and are noticeable in the medium to long term. The effects may vary depending on each patient’s individual profile and the overall protocol followed.
Increased energy and vitality
Some patients report more energy in the following weeks. No trials confirm this in healthy people, and results vary.
Mental clarity
Some patients report clearer thinking. It is an individual perception and has not been shown in trials.
Better regenerative response
No studies show that plasmapheresis improves the response to other treatments. We assess this in consultation.
Reduction of systemic inflammation
Low-grade chronic inflammation is linked to accelerated aging and many chronic diseases. We can measure inflammation markers in your blood tests before and after. A drop does not, on its own, mean a benefit for your health.
Liver and kidneys
There are no data showing that plasmapheresis improves liver or kidney function in healthy people. Your specialist reviews your blood tests before proposing it.
How many sessions
We recommend one session a year, together with the habits of the Monarka Plan. Published studies used several sessions, and no data show that a single one gives the same changes.
⸻ Frequently Asked Questions
Everything you need to know
Is plasmapheresis the same as plasma exchange?
How long does a plasmapheresis session last?
The duration depends on individual factors such as weight, height, and hematocrit. Generally, each session lasts between 60 and 100 minutes, with a maximum of approximately 2 hours. Recovery is immediate: you can resume your normal activities the same day without needing to rest.
How many sessions are recommended?
As part of a longevity plan, one session per year is typically recommended for maintenance. The exact number and frequency of sessions are determined during the initial medical assessment, based on the patient’s health status, goals, and overall protocol.
Is it a safe treatment?
It is an established medical procedure, but it has risks. The most common are a bruise at the puncture site, dizziness or a drop in blood pressure, and tingling around the lips from the anticoagulant. Infection, allergic reactions and bleeding are uncommon. That is why we carry out an assessment first and there is medical supervision throughout the session. The specialist also rules out, beforehand, situations in which it is not recommended. More detail in our guide to the risks and evidence of plasmapheresis.
Do I need to prepare beforehand?
The Monarka medical team will provide you with specific guidelines during your initial assessment. Generally, adequate hydration is recommended, and you should avoid fasting. A preliminary blood test is performed to confirm that the treatment is appropriate and to tailor the protocol to your individual needs.
How does it fit into the Monarka Plan?
Plasmapheresis is not a mandatory or automatic step in the Monarka Plan, but rather a tool that the longevity specialist prescribes when it is indicated for your individual profile. After the initial assessment—which includes blood tests if necessary—the doctor determines whether and when it makes sense to incorporate it. When indicated, it fits in with the other protocols in the plan: precision nutrition, supplementation, IHHT, and cell therapies.
How much does plasmapheresis cost at Monarka?
The price of a plasmapheresis session at Monarka Clinic is €5,000. This price includes the initial consultation with our longevity specialist, any necessary blood tests if the medical team deems them appropriate, and the complete plasmapheresis session. There are no hidden costs or additional charges.
What is the difference between this and a conventional "detox" or purification?
Plasmapheresis is a medical procedure: part of the plasma is removed and replaced with albumin. A diet or a “detox” supplement does not do that. But that does not mean it is better for your health: in healthy people, the benefits have not been shown yet. “Detox” products do not have solid evidence either.
Assessment included in the treatment
The plasmapheresis session at Monarka includes a prior consultation with our longevity specialist: we evaluate your profile, review your history, and design how to integrate the treatment into your personal Monarka Plan.
Total price · All inclusive
- Assessment with a longevity specialist
- Preliminary analysis if applicable
- Complete plasmapheresis session
5.000 €
Response in less than 24 hours
Is plasmapheresis
the tool
you need?
There’s only one way to know: an assessment with our longevity specialist. When it’s indicated, it can be a good option. When it’s not, we’ll tell you.